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Daniel M Commane

Senior Lecturer, Nutritional Sciences

Department: Applied Sciences

PhD, Investigating the effects of probiotics and prebiotics in colorectal cancer risk. Ulster University (2004)

Post doctoral training, Diet-related biomarkers of colorectal cancer risk. Newcastle University (2005-2009)

Lecturer- Nutritional Science, University of Chester (2009-10)

Lecturer-Nutritional Science, University of Reading (2010-2018)

Campus Address

Ellison Building 324



0191 227 7984

Qualifications

PhD, PG Cert (HEd) BSc hons. FHEA, RNutr

Research Themes and Scholarly Interests

Research interests in the areas of diet, the gut microbiota and health, notably in relation to cancer risk but also appetite regulation. Other areas of research activity include studies of plant polyphenols and health. 

Current and Recent Projects

  • Flax phytoestrogens and menopausal health, Saudi ministry of Health (PhD studentship 2015) (PI)
  • Evaluating the potential influence of watercress isothiocyanate exposure on treatment outcomes in breast cancer (PhD studentship 2014) (CoI)
  • Proteolytic microbial metabolites as carcinogens in the human colon (The Sultanate of Oman, PhD studentship) (PI)
  • The health benefits of consuming Acai (PhD studentship, Saudi Ministry of Health) (PI)
  • ADAS Ltd. Post market monitoring for the safety of GM crops £6400 (2014)  (CoI)
  • Comvita Ltd: Olive polyphenols and metabolic disease risk. £40000, (2013) (as PI) CoI’s, Ian Rowland and Jeremy Spencer
  • Herbalife Ltd: Prebiotics and satiety £100000 (2013) (as PI), (CoI’s Glenn Gibson and Orla Kennedy)
  • Rocquette: Prebiotics and satiety £126000 (2016) (CoI) (Orla Kennedy PI)
  • University of Chester, Small Research Grants: Investigating the estrogenic activity of enterolactone on breast, adipocyte and bone cell lines. £21 000 (2009) (as PI)

Key Publications and Outputs

Hobden MR, Guérin-Deremaux L, Commane DM, Rowland IR, Gibson GR, Kennedy OB Optimisation of methods for a satiety preload study. Pilot Feasibility Stud. (2017) 17;3:61.

Saibandith B, Spencer JPE, Rowland IR, and Commane DM. Olive Polyphenols and the Metabolic Syndrome. Molecules. (2017) 29;22-27.

Alqurashi RMM, Alarifi SN, Walton GE, Costabile A, Rowland IR and  Commane DM. The Influence of Acai on a Simulated Model of Gastrointestinal Digestion and Colonic Fermentation. Journal of Food Chemistry. (2017) 234:190-198

Alqurashi RM, Galante LA, Rowland IR, Spencer JPE, and Commane DM. Consumption of a flavonoid-rich açai meal is associated with acute improvements in vascular function and a reduction in total oxidative status in healthy overweight men Am J Clin Nutr, (2016) 104(5):1227-1235.

Méplan C, Johnson IT, Polley AC, Cockell S, Bradburn DM, Commane DM, Arasaradnam RP, Mulholland F, Zupanic A, Mathers JC, Hesketh J. Transcriptomics and proteomics show that selenium affects inflammation, cytoskeleton, and cancer pathways in human rectal biopsies. FASEB J. (2016) 30(8):2812-25.

Greaves LC, Nooteboom M, Elson JL, Tuppen HA, Taylor GA, Commane DM, Arasaradnam RP, Khrapko K, Taylor RW, Kirkwood TB, Mathers JC, Turnbull DM. Clonal expansion of early to mid-life mitochondrial DNA point mutations drives mitochondrial dysfunction during human ageing. PLoS Genet. (2014) Sep 18;10(9): 

PGR Supervision

8 PhD students supervised 7 as PI, 5 to completion


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