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Dr Meera Soundararajan

Senior Lecturer

Department: Applied Sciences

Dr Meera Soundararajan is a Senior Lecturer in Biomedical Sciences who joined Northumbria University in 2011. 

Meera’s work during her PhD involved elucidating the mechanism of DNA interacting and modifying enzymes.  Her initial post-doctoral work was directed towards understanding the transcriptional regulation in Acute Myeloid Leukemia through characterising macromolecular assemblages on the promoter. She continued to work as a postdoctoral fellow at Oxford which involved structural and functional characterisation of signalling molecules belonging to receptor mediated and Phosphorylation dependent signalling pathways that directly involved pathogenesis of cancer and development of neurological disorders.

Meera Soundararajan

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia, Szoltysek, K., Ciardullo, C., Zhou, P., Walaszczyk, A., Willmore, E., Rand, V., Marshall, S., Hall, A., J. Harrison, C., Eswaran, J., Soundararajan, M. 16 Oct 2020, In: International Journal of Molecular Sciences
  • Homozygous Southeast Asian Ovalocytosis in five live-born neonates, Lavinya, A., Razali, R., Razak, M., Mohamed, R., Moses, E., Soundararajan, M., Bruce, L., Eswaran, J., Yusoff, N. 12 Nov 2020, In: Haematologica
  • Novel 1‑hydroxypyridin‑2‑one metal chelators prevent and rescue ubiquitin proteasomal‑related neuronal injury in an in vitro model of Parkinson’s disease, Lewis, F., Farooz, S., Elson, J., Hubscher-Bruder, V., Brandel, J., Soundararajan, M., Smith, D., Dexter, D., Tetard, D., Pienaar, I. Mar 2020, In: Archives of Toxicology
  • Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort, Zakaria, Z., Zulkifle, M., Wan Hasan, W., Azhari, A., Abdul Raub, S., Eswaran, J., Soundararajan, M., Syed Husain, S. 20 Sep 2019, In: OncoTargets and Therapy
  • Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases, Kay, L., Sangal, V., Black, G., Soundararajan, M. 1 Jan 2019, In: Molecular and Cellular Biochemistry
  • Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism, Peters, D., Kay, L., Eswaran, J., Lakey, J., Soundararajan, M. 2 Dec 2018, In: International Journal of Molecular Sciences
  • Understanding Miro GTPases: Implications in the Treatment of Neurodegenerative Disorders, Kay, L., Pienaar, I., Cooray, R., Black, G., Soundararajan, M. 1 Sep 2018, In: Molecular Neurobiology
  • Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia, Ciardullo, C., Zhou, P., Willmore, E., Harrison, C., Hall, A., Eswaran, J., Soundararajan, M. 12 Apr 2016, 36th World Congress of the International Society of Hematology
  • Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A, Kay, L., Smulders-Srinivasan, T., Soundararajan, M. 9 Aug 2016, Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods, London, Elsevier
  • Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition, Soundararajan, M., Roos, A., Savitsky, P., Filippakopoulos, P., Kettenbach, A., Olsen, J., Gerber, S., Eswaran, J., Knapp, S., Elkins, J. 2013, In: Structure

PGR Supervision

Laura Kay Characterisation of Atypical Human GTPases: Elucidation of Molecular Functions and Interactors Start Date: 01/10/2012 End Date: 10/11/2017


  • Biochemistry PhD June 30 2002
  • Fellow (FHEA) Higher Education Academy (HEA) 2014
  • Information not provided Biochemical Society 2011

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