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Dr Vartul Sangal

Senior Lecturer

Department: Applied Sciences

Dr Sangal completed his Ph.D. at the Max-Planck Institute for Infection Biology, Berlin followed by postdoctoral research at the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow. He established his independent research at Northumbria University as an Anniversary Research Fellow and was appointed as a Senior Lecturer in Cellular and Molecular Sciences in September 2016.

Dr Sangal works in collaboration with many research groups both nationally and internationally and delivered invited talks in several international conferences.

Vartul Sangal

Research Themes and Scholarly Interests

Dr Sangal is interested in evolutionary and genetic analysis of whole genome sequences of bacteria and microbial community analysis of soil samples from challenging environments using computational approaches. His group works on identification and characterisation of novel virulence genes in pathogenic bacteria using molecular techniques. His research also emphasises the importance of incorporating genome sequence-based approaches into systematics for a reliable identification and classification of prokaryotic taxa.

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae, Will, R., Ramamurthy, T., Sharma, N., Veeraraghavan, B., Sangal, L., Haldar, P., Pragasam, A., Vasudevan, K., Kumar, D., Das, B., Heinz, E., Melnikov, V., Baker, S., Sangal, V., Dougan, G., Mutreja, A. 8 Mar 2021, In: Nature Communications
  • Insights into old and new foes: Pan-genomics of Corynebacterium diphtheriae and Corynebacterium ulcerans, Sangal, V., Burkovski, A. 2020, Pan-genomics: Applications, Challenges, and Future Prospects, Academic Press
  • Phylogenomic characterisation of a novel corynebacterial species pathogenic to animals, Möller, J., Musella, L., Melnikov, V., Geißdörfer, W., Burkovski, A., Sangal, V. 1 Aug 2020, In: Antonie van Leeuwenhoek
  • Phylogenomic Classification and Biosynthetic Potential of the Fossil Fuel-Biodesulfurizing Rhodococcus Strain IGTS8, Thompson, D., Cognat, V., Goodfellow, M., Koechler, S., Heintz, D., Carapito, C., Van Dorsselaer, A., Mahmoud, H., Sangal, V., Ismail, W. 7 Jul 2020, In: Frontiers in Microbiology
  • Streptomyces alkaliterrae sp. nov., isolated from an alkaline soil, and emended descriptions of Streptomyces alkaliphilus, Streptomyces calidiresistens and Streptomyces durbertensis, Świecimska, M., Golińska, P., Nouioui, I., Wypij, M., Rai, M., Sangal, V., Goodfellow, M. Nov 2020, In: Systematic and Applied Microbiology
  • Genomic analysis of a novel nontoxigenic Corynebacterium diphtheriae strain isolated from a cancer patient, Ramdhan, N., Blom, J., Sutcliffe, I., Pereira-Ribeiro, P., Santos, C., Mattos-Guaraldi, A., Burkovski, A., Sangal, V. 1 Jul 2019, In: New Microbes and New Infections
  • Genomic analysis of a novel Rhodococcus (Prescottella) equi isolate from a bovine host, Paterson, M., Ranasinghe, D., Blom, J., Dover, L., Sutcliffe, I., Lopes, B., Sangal, V. 13 Jul 2019, In: Archives of Microbiology
  • Genomic Insights Into Plant-Growth-Promoting Potentialities of the Genus Frankia, Nouioui, I., Cortés-albayay, C., Carro, L., Castro, J., Gtari, M., Ghodhbane-Gtari, F., Klenk, H., Tisa, L., Sangal, V., Goodfellow, M. 4 Jul 2019, In: Frontiers in Microbiology
  • Mycolicibacterium stellerae sp. nov., a rapidly growing scotochromogenic strain isolated from Stellera chamaejasme, Nouioui, I., Sangal, V., Cortés-Albayay, C., Jando, M., Igual, J., Klenk, H., Zhang, Y., Goodfellow, M. 1 Nov 2019, In: International Journal of Systematic and Evolutionary Microbiology
  • Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases, Kay, L., Sangal, V., Black, G., Soundararajan, M. 1 Jan 2019, In: Molecular and Cellular Biochemistry

Professional Activity

  • Please visit the Pure Research Information Portal for further information
  • Invited talk: London Interdisciplinary Biosciences Consortium (LIDo) Lecture Week: Impact of vaccine on evolutionary dynamics of human pathogen Corynebacterium diphtheriae 2021
  • Invited talk: Influence of vaccine on evolution of Corynebacterium diphtheriae 2020
  • Oral presentation: Application of whole genome sequencing to exploring intra-generic heterogeneity 2018
  • Invited talk: Does vaccine drive the evolution of Corynebacterium diphtheriae? 2017
  • Invited talk: Is vaccine driving the evolution of Corynebacterium diphtheriae? 2017
  • Invited talk: From genes to genome: a paradigm shift in inferring evolution, epidemiology and genetics of virulence in pathogenic bacteria 2015
  • Oral presentation: Revolutionizing prokaryotic systematics through next-generation sequencing: Rhodococcus as a case study 2015
  • Invited talk: Unique evolutionary histories and genetic basis of biochemical properties and virulence in Corynebacterium diphtheriae 2014
  • Oral presentation: Identification, evolution and epidemiology of pathogenic bacteria – from genes to genomes 2014
  • Oral presentation: Whole genome analyses support the taxonomic separation of “Rhodococcus equi” from other rhodococci 2014

PGR Supervision

  • Megan Paterson Molecular Characterisation of Novel Pathways for Cell Envelope Protein Localisation in Rhodococcus equi Start Date: 01/10/2017
  • Megan Paterson Start Date: 01/10/2017 End Date: 02/03/2021

Qualifications

  • Molecular Biology PhD October 01 2008
  • Fellow (FHEA) Higher Education Academy (HEA) 2016


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