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Dr David Tetard

Senior Lecturer

Department: Applied Sciences


Dr David Tétard studied at the University of Bordeaux 1 (France) and completed his PhD there in 1996, under the supervision of Prof. J.-B. Verlhac. The work related to the synthesis and study of iron and manganese complexes as oxidation catalysts. He then undertook post-doctoral work in the laboratory of Prof. Dave Leigh, then at UMIST (Manchester, UK), working on molecular recognition. After a brief time at Oxford Diversity (now part of Evotec), Dr David Tétard joined Unilever Research and Development at Port Sunlight (UK) where he worked for household and personal care products for 9 years (primarily on Laundry, Hair and Deodorant products). In November 2007, he joined Northumbria University where he’s now a senior lecturer, teaching organic, inorganic and physical chemistry. His expertise includes: organic synthesis, co-ordination chemistry, oxidation chemistry, bacterial enzyme inhibition and keratin chemistry.

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • Anticancer activity of a novel methylated analogue of L-mimosine against an in vitro model of human malignant melanoma, Kyriakou, S., Mitsiogianni, M., Mantso, T., Cheung, W., Todryk, S., Veuger, S., Pappa, A., Tetard, D., Panagiotidis, M. 1 Jun 2020, In: Investigational New Drugs
  • Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants, Gutbier, S., Kyriakou, S., Schildknecht, S., Ückert, A., Brüll, M., Lewis, F., Dickens, D., Pearson, L., Elson, J., Michel, S., Hubscher-Bruder, V., Brandel, J., Tetard, D., Leist, M., Pienaar, I. 1 Sep 2020, In: Archives of Toxicology
  • Novel 1‑hydroxypyridin‑2‑one metal chelators prevent and rescue ubiquitin proteasomal‑related neuronal injury in an in vitro model of Parkinson’s disease, Lewis, F., Farooz, S., Elson, J., Hubscher-Bruder, V., Brandel, J., Soundararajan, M., Smith, D., Dexter, D., Tetard, D., Pienaar, I. Mar 2020, In: Archives of Toxicology
  • The influence of linkages between 1-Hydroxy-2(1H)-pyridinone Coordinating Groups and a Tris(2-aminoethyl)amine core in a novel series of synthetic Hexadentate Iron(III) Chelators on antimicrobial activity, Workman, D., Hunter, M., Wang, S., Brandel, J., Hubscher, V., Dover, L., Tetard, D. 1 Jan 2020, In: Bioorganic Chemistry
  • An Overview of Multifunctional Metal Chelators as Potential Treatments for Neurodegenerative Diseases, Lewis, F., Tetard, D. May 2017, Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics, San Diego, Elsevier
  • Metal chelating compounds for use in treating diseases, Tetard, D., Lewis, F. 26 May 2016
  • Synthesis of novel Iron(III) chelators based on triaza macrocycle backbone and 1-hydroxy-2(H)-pyridin-2-one coordinating groups and their evaluation as antimicrobial agents, Workman, D., Hunter, M., Dover, L., Tetard, D. Jul 2016, In: Journal of Inorganic Biochemistry
  • Epoxidation of Strained Alkenes Catalysed by (1,2-dimethyl-4(1H)pyridinone-3-olate)2MnIIICl, Robinson-Miller, A., Wyatt, M., Tetard, D. Mar 2015, In: Journal of Molecular Catalysis A: Chemical
  • Protection from neurodegeneration in the 6-hydroxydopamine (6-OHDA) model of Parkinson's with novel 1-hydroxypyridin-2-one metal chelators, Workman, D., Tsatsanis, A., Lewis, F., Boyle, J., Mousadoust, M., Hettiarachchi, N., Hunter, M., Peers, C., Tetard, D., Duce, J. 13 May 2015, In: Metallomics : Integrated Biometal Science

PGR Supervision

Sotiris Kyriakou Synthesis and Biological Evaluation of Metal Chelators of the Hydroxypyridinone Family as Potential Treatment of Parkinson’s Disease and Cancer Start: 01/10/2016

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