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Dr Meng Zhang

Senior Lecturer

Department: Applied Sciences

 

Meng studied for her BSc in Biotechnology at ShanDong Agriculture University, China, between 1997-2001, which included a half year research project at Shandong Academy of Agricultural Science. Meng came to England and study for a Masters degree in Health, Environment and Development at Sunderland University between 2001 and 2002. She was then rewarded Overseas Research Scholarship by UK Universities, and studied her PhD in Proteomics research in Northumbria University under the supervision of Prof. Gary Black. After her PhD, Meng stayed in Northumbria University  as a Post-doctoral Research Associate and continually worked on Proteomics for 1 year. At end of 2007, Meng started as R&D manager in Nzomics Biocatalysis, which is a university enterprise in Northumbria. Based on her commercial experience, Meng did a part-time MBA in Newcastle Business School. From 2010, Meng began lecturing in Biomedical Sciences.

Academically, Meng has published several papers in both Proteomics and Molecular Biology. She has successfully supervised one Master of Research students independently and co-supervised several PhD students. Meng has successfully completed one Knowledge Transfer Partnership (KTP) project, and two Innovation Vouchers projects. In addition, she has managed many commercial research projects in Nzomics for national and international clients including GSK, Kraft Foods, Almac Sciences, Prozomix, and Hycagen.

Meng’s research interests revolve around (a) the expression of recombinant enzymes in Escherichia coli  and Pichia Pastoris and their biochemical and structural characterisation and (b) proteomics, including the development of advanced methods in Proteomics  research and study of pathogenic virulence factors. Specifically Meng is interested in biocatalysis enzymes such as nitrile hydratases, nitrilases, amidases, lipases, glycosyl transferases and cytochrome P450s; and biofuel /biorefinery enzymes such as xylanases, and carbohydrate-active enzymes in general such as hyaluronate lyases and pectate lyases. Proteomic research is focussed on study of streptococcal pathogens virulence factors, and developing 2 dimensional LC based method. Meng is also interested in understanding the heterogeneity of recombinant proteins expressed in E. coli.

Meng Zhang

Campus Address

EBA501
Ellison Building


Qualifications

  • Business and Administration MBA July 06 2011
  • Biomedical Science PhD November 13 2006
  • Health MA September 01 2001
  • Full Ordinary Member Society for Applied Microbiology (SfAM) 2002

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • Acupuncture as a multifunctional neuroprotective therapy ameliorates cognitive impairment in a rat model of vascular dementia, Yang, J., Wang, X., Zhang, M., Xiao, L., Zhu, W., Ji, C., Liu, C. 11 Nov 2018, In: CNS Neuroscience and Therapeutics
  • Design and modelling of an engineered bacteria-based, pressure-sensitive soil, Dade-robertson, M., Mitrani, H., Corral, J., Zhang, M., Hernan, L., Guyet, A., Wipat, A. 24 May 2018, In: Bioinspiration and Biomimetics
  • Mild hydrostatic pressure triggers oxidative responses in Escherichia coli, Guyet, A., Dade-Robertson, M., Wipat, A., Casement, J., Smith, W., Mitrani, H., Zhang, M. 17 Jul 2018, In: PLoS One
  • Architects of nature, Dade-Robertson, M., Keren-Paz, A., Zhang, M., Kolodkin-Gal, I. 1 Sep 2017, In: Microbial Biotechnology
  • Synthetic Biological Construction: Beyond ‘bioinspired’ in the design of new materials and fabrication systems, Dade-Robertson, M., Rodriguez Corral, R., Guyet, A., Mitrani, H., Wipat, A., Zhang, M. Jun 2017
  • Thinking Soils: a synthetic biology approach to material-based design computation, Dade-Robertson, M., Corral, J., Mitrani, H., Zhang, M., Wipat, A., Ramirez-Figueroa, C., Hernan, L. 29 Oct 2016
  • A high-throughput screening method for determining the substrate scope of nitrilases, Black, G., Brown, N., Perry, J., Randall, P., Turnbull, G., Zhang, M. 9 Jan 2015, In: Chemical Communications
  • Characterisation of SEQ0694 (PrsA/PrtM) of Streptococcus equi as a functional peptidyl-prolyl isomerase affecting multiple secreted protein substrates, Ikolo, F., Zhang, M., Harrington, D., Robinson, C., Waller, A., Sutcliffe, I., Black, G. 1 Dec 2015, In: Molecular BioSystems
  • Material ecologies for synthetic biology, Dade-Robertson, M., Ramirez-Figueroa, C., Zhang, M. 1 Mar 2015, In: Computer-Aided Design
  • Changes in immunoreactive terminals containing serotonin, substance P, vesicular glutamate transporter 2 and corticotropin-releasing factor in the lumbosacral spinal cord of aged C56BL/6J male mice, Tsang, H., Zhang, M., Black, G., Saffrey, M., Ranson, R. 7 Jul 2014

PGR Supervision

  • Jamie Haystead Start: 01/10/2018
  • Nicola Cowley Start: 13/08/2019
  • Jennifer Wright Start: 01/10/2016
  • Jenifer Mariya Francis The Study Of Streptococcal Pathogenesis using Proteomic and Metabolomic Approaches Start: 08/12/2015


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