Dr Meera Soundararajan

Assistant Professor

Department: Applied Sciences

Dr Meera Soundararajan is a Senior Lecturer in Biomedical Sciences who joined Northumbria University in 2011.

Meera’s work during her PhD involved elucidating the mechanism of DNA interacting and modifying enzymes. Her initial post-doctoral work was directed towards understanding the transcriptional regulation in Acute Myeloid Leukemia through characterising macromolecular assemblages on the promoter. She continued to work as a postdoctoral fellow at Oxford which involved structural and functional characterisation of signalling molecules belonging to receptor mediated and Phosphorylation dependent signalling pathways that directly involved pathogenesis of cancer and development of neurological disorders.

Email Meera

Key Publications

Please visit the Pure Research Information Portal for further information
Low bach2 expression predicts adverse outcome in chronic lymphocytic leukaemia, Ciardullo, C., Szoltysek, K., Zhou, P., Pietrowska, M., Marczak, L., Willmore, E., Enshaei, A., Walaszczyk, A., Ho, J., Rand, V., Marshall, S., Hall, A., Harrison, C., Soundararajan, M., Eswaran, J. 21 Dec 2021, In: Cancers
DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia, Szoltysek, K., Ciardullo, C., Zhou, P., Walaszczyk, A., Willmore, E., Rand, V., Marshall, S., Hall, A., J. Harrison, C., Eswaran, J., Soundararajan, M. 16 Oct 2020, In: International Journal of Molecular Sciences
Homozygous Southeast Asian Ovalocytosis in five live-born neonates, Lavinya, A., Razali, R., Razak, M., Mohamed, R., Moses, E., Soundararajan, M., Bruce, L., Eswaran, J., Yusoff, N. 12 Nov 2020, In: Haematologica
Novel 1‑hydroxypyridin‑2‑one metal chelators prevent and rescue ubiquitin proteasomal‑related neuronal injury in an in vitro model of Parkinson’s disease, Lewis, F., Farooz, S., Elson, J., Hubscher-Bruder, V., Brandel, J., Soundararajan, M., Smith, D., Dexter, D., Tetard, D., Pienaar, I. 1 Mar 2020, In: Archives of Toxicology
Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort, Zakaria, Z., Zulkifle, M., Wan Hasan, W., Azhari, A., Abdul Raub, S., Eswaran, J., Soundararajan, M., Syed Husain, S. 20 Sep 2019, In: OncoTargets and Therapy
Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases, Kay, L., Sangal, V., Black, G., Soundararajan, M. 1 Jan 2019, In: Molecular and Cellular Biochemistry
Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism, Peters, D., Kay, L., Eswaran, J., Lakey, J., Soundararajan, M. 2 Dec 2018, In: International Journal of Molecular Sciences
Understanding Miro GTPases: Implications in the Treatment of Neurodegenerative Disorders, Kay, L., Pienaar, I., Cooray, R., Black, G., Soundararajan, M. 1 Sep 2018, In: Molecular Neurobiology
Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia, Ciardullo, C., Zhou, P., Willmore, E., Harrison, C., Hall, A., Eswaran, J., Soundararajan, M. 12 Apr 2016, 36th World Congress of the International Society of Hematology
Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A, Kay, L., Smulders-Srinivasan, T., Soundararajan, M. 9 Aug 2016, Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods, London, Elsevier

PGR Supervision

Laura Kay Characterisation of Atypical Human GTPases: Elucidation of Molecular Functions and Interactors Start Date: 01/10/2012 End Date: 10/11/2017

Qualifications

Biochemistry PhD June 30 2002
Fellow (FHEA) Higher Education Academy (HEA) 2014
Information not provided Biochemical Society 2011

+

Northumbria Open Days

Open Days are a great way for you to get a feel of the University, the city of Newcastle upon Tyne and the course(s) you are interested in.

+

Research at Northumbria

Research is the life blood of a University and at Northumbria University we pride ourselves on research that makes a difference; research that has application and affects people's lives.