Skip navigation

Dr Meera Soundararajan

Senior Lecturer

Department: Applied Sciences

Dr Meera Soundararajan is a Senior Lecturer in Biomedical Sciences who joined Northumbria University in 2011. 

Meera’s work during her PhD involved elucidating the mechanism of DNA interacting and modifying enzymes.  Her initial post-doctoral work was directed towards understanding the transcriptional regulation in Acute Myeloid Leukemia through characterising macromolecular assemblages on the promoter. She continued to work as a postdoctoral fellow at Oxford which involved structural and functional characterisation of signalling molecules belonging to receptor mediated and Phosphorylation dependent signalling pathways that directly involved pathogenesis of cancer and development of neurological disorders.


  • Biochemistry PhD June 30 2002
  • Fellow (FHEA) Higher Education Academy (HEA) 2014
  • Information not provided Biochemical Society 2011

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases, Kay, L., Sangal, V., Black, G., Soundararajan, M. 1 Jan 2019, In: Molecular and Cellular Biochemistry
  • Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism, Peters, D., Kay, L., Eswaran, J., Lakey, J., Soundararajan, M. 2 Dec 2018, In: International Journal of Molecular Sciences
  • Understanding Miro GTPases, Kay, L., Pienaar, I., Cooray, R., Black, G., Soundararajan, M. 1 Sep 2018, In: Molecular Neurobiology
  • Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A, Kay, L., Smulders-Srinivasan, T., Soundararajan, M. 9 Aug 2016, Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods, London, Elsevier
  • Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia, Ciardullo, C., Zhou, P., Willmore, E., Harrison, C., Hall, A., Eswaran, J., Soundararajan, M. 12 Apr 2016, 36th World Congress of the International Society of Hematology
  • Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition, Soundararajan, M., Roos, A., Savitsky, P., Filippakopoulos, P., Kettenbach, A., Olsen, J., Gerber, S., Eswaran, J., Knapp, S., Elkins, J. 2013, In: Structure
  • Atypical GTPases as drug targets, Soundararajan, M., Eswaran, J. 2012, In: Anti-Cancer Agents in Medicinal Chemistry
  • Leucettines, a Class of Potent Inhibitors of cdc2-Like Kinases and Dual Specificity, Tyrosine Phosphorylation Regulated Kinases Derived from the Marine Sponge Leucettamine B: Modulation of Alternative Pre-RNA Splicing, Debdab, M., Carreaux, F., Renault, S., Soundararajan, M., Fedorov, O., Filippakopoulos, P., Lozach, O., Babault, L., Tahtouh, T., Baratte, B., Ogawa, Y., Hagiwara, M., Eisenreich, A., Rauch, U., Knapp, S., Meijer, L., Bazureau, J. 26 May 2011, In: Journal of Medicinal Chemistry
  • Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function, Kwiatkowski, N., Jelluma, N., Filippakopoulos, P., Soundararajan, M., Manak, M., Kwon, M., Choi, H., Sim, T., Deveraux, Q., Rottmann, S., Pellman, D., Shah, J., Kops, G., Knapp, S., Gray, N. 2010, In: Nature Chemical Biology
  • Structural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2), Kimple, A., Soundararajan, M., Hutsell, S., Roos, A., Urban, D., Setola, V., Temple, B., Roth, B., Knapp, S., Willard, F., Siderovski, D. 17 Jul 2009, In: Journal of Biological Chemistry

PGR Supervision

Laura Kay Characterisation of Atypical Human GTPases: Elucidation of Molecular Functions and Interactors Start: 01/10/2012


Northumbria Open Days

Open Days are a great way for you to get a feel of the University, the city of Newcastle upon Tyne and the course(s) you are interested in.

Research at Northumbria

Research at Northumbria

Research is the life blood of a University and at Northumbria University we pride ourselves on research that makes a difference; research that has application and affects people's lives.


Order your prospectus

If you would like to know more about our courses, or life in general as a student at Northumbria, then we can help you.

Latest News and Features

More news

Back to top