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Dr Gerrit Hilgen

Senior Lecturer

Department: Applied Sciences

Gerrit Hilgen started his first academic position as Senior Lecturer in the department of Applied Sciences in 2020. He is interested in neuronal signal processing, functional and structural imaging, as well as scientific computing with a focus on the mature and neonatal retina in health and disease and human retinal organoids. His research is internationally recognised as evidenced by frequent invitations for oral presentations and many peer-reviewed publications in high prestige journals. Gerrit has successfully spearheaded interdisciplinary research projects and led a scientific consultancy in an industrial collaboration. 

Gerrit is involved in projects including transplantation of photoreceptor precursors at early and advanced stages of retinal degeneration to restore vision, as well as projects deciphering novel synapse forming mechanisms and ocular channelopathies. His recent study used a combination of cell labelling with high resolution microscopy and electrophysiology to decipher new groups of neurons that share a common gene expression. Gerrit’s ambition is to build a world-leading laboratory that bridges between various disciplines including bio(medical)science, cellular imaging, multi-omics/multimodal, and computational approaches. 

He is designing and delivering learning & teaching content for the BSc Biology & BSc Biomedical programme in the department of Applied Sciences. He is the module leader for the level 6 module “Neuroscience in Practice” and lecturer/practical instructor on several other biology/biomedical modules. His module develops knowledge and understanding of current techniques involved in neuroscience but also applied professional skills e.g., group work, critical thinking and providing feedback.

Gerrit Hilgen

Key Publications

  • Please visit the Pure Research Information Portal for further information
  • A novel approach to the functional classification of retinal ganglion cells, Hilgen, G., Kartsaki, E., Kartysh, V., Cessac, B., Sernagor, E. Mar 2022, In: Open Biology
  • Transplanted pluripotent stem cell-derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration, Zerti, D., Hilgen, G., Dorgau, B., Collin, J., Ader, M., Armstrong, L., Sernagor, E., Lako, M. 3 Mar 2021, In: Stem Cells
  • Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency, Hallam, D., Hilgen, G., Dorgau, B., Zhu, L., Yu, M., Bojic, S., Hewitt, P., Schmitt, M., Uteng, M., Kustermann, S., Steel, D., Nicholds, M., Thomas, R., Treumann, A., Porter, A., Sernagor, E., Armstrong, L., Lako, M. 1 Oct 2018, In: Stem Cells
  • Unsupervised Spike Sorting for Large-Scale, High-Density Multielectrode Arrays, Hilgen, G., Sorbaro, M., Pirmoradian, S., Muthmann, J., Kepiro, I., Ullo, S., Ramirez, C., Puente Encinas, A., Maccione, A., Berdondini, L., Murino, V., Sona, D., Cella Zanacchi, F., Sernagor, E., Hennig, M. 7 Mar 2017, In: Cell Reports
  • Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina, Hilgen, G., Pirmoradian, S., Pamplona, D., Kornprobst, P., Cessac, B., Hennig, M., Sernagor, E. Mar 2017, In: Scientific Reports

Professional Activity

  • Please visit the Pure Research Information Portal for further information
  • Invited talk: A novel approach to the functional classification of retinal ganglion cells 2021
  • Invited talk: Understanding global retinal function: from mice to humans 2021
  • Oral presentation: A novel approach to the functional classification of retinal ganglion cells 2021
  • Invited talk: A novel approach to the functional classification of retinal ganglion cells 2020
  • Consultancy: Large-scale recordings of retinal organoids 2020
  • Editorial work: Frontiers in Cellular Neuroscience (Journal) 2020

Qualifications

  • Neurosciences PhD June 07 2012
  • Full Member Anatomical Society 2018
  • Full Member Physiological Society 2016


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